philipn authored on Oct. 22, 2020, 8:41 p.m. | | Additions are marked like this |
Colchicine, a drug used to treat gout, has been proposed as a COVID-19 therapeutic. COVID-19 trialsInterim analysis of a small number of participants (n=35) in a randomized, double-blind, placebo controlled trial of colchicine showed hints of promise: The use of colchicine reduced the length of both, supplemental oxygen therapy and hospitalization. Shortly less than half of the patients of the Colchicine group stopped receiving supplemental oxygen until day 2. Clinical improvement was in parallel with a reduction on serum levels of C-reactive protein. ..Clinical trials with larger numbers of patients should be conducted to further evaluate the efficacy and safety of colchicine as an adjunctive therapy for hospitalized patients with moderate to severe COVID-19. In March of 2020, the "Colchicine Coronavirus SARS-CoV2 Trial (COLCORONA)" trial of colchinine for COVID-19 began. It aims to enroll 6,000 COVID-19 positive patients via an internet-enrollment (remote) approach. See also | 
Colchicine, a drug used to treat gout, has been proposed as a COVID-19 therapeutic. COVID-19 trialsInterim analysis of a small number of participants (n=35) in a randomized, double-blind, placebo controlled trial of colchicine showed hints of promise: The use of colchicine reduced the length of both, supplemental oxygen therapy and hospitalization. Shortly less than half of the patients of the Colchicine group stopped receiving supplemental oxygen until day 2. Clinical improvement was in parallel with a reduction on serum levels of C-reactive protein. ..Clinical trials with larger numbers of patients should be conducted to further evaluate the efficacy and safety of colchicine as an adjunctive therapy for hospitalized patients with moderate to severe COVID-19. In March of 2020, the "Colchicine Coronavirus SARS-CoV2 Trial (COLCORONA)" trial of colchinine for COVID-19 began. It aims to enroll 6,000 COVID-19 positive patients via an internet-enrollment (remote) approach. See also |
