TOGETHER Trial - Encycla

philipn authored on March 23, 2022, 8:08 a.m.

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The TOGETHER Trial is a clinical trial platform evaluating repurposed drugs for early treatment of COVID-19. The TOGETHER Trial's aim is to discover if existing medications can be used to treat people with early-diagnosed COVID-19. The TOGETHER Trial was initiated on June of 2020. On January 20, 2021, TOGETHER enrolled its first patient. The TOGETHER Trial is a multi-platform, randomized, adaptive trial. The co-principal investigators of TOGETHER are Dr. Edward Mills and Dr. Gilmar Reis. Drugs trialed Hydroxychloroquine - effect not found, arm stopped. See trial results paper. Lopinavir/Ritonavir - effect not found, arm stopped. See trial results paper. Ivermectin - effect not found, arm stopped. Metformin - effect not found, arm stopped. See trial results paper. Fluvoxamine - intervention found effective. See trial results paper. Peginterferon Lambda - intervention found effective. Doxazosin - recruitment paused. Links togethertrial.com - website for the TOGETHER trial. Includes trial protocol design, statistical analysis plan and other information. TOGETHER Trial on Twitter.	The TOGETHER Trial did not find hydroxychloroquine or lopinavir/ritonavir effective in reducing the need for hospitalization. Photo CC-BY Reis G et al. The TOGETHER Trial is a clinical trial platform evaluating repurposed drugs for early treatment of COVID-19. The TOGETHER Trial's aim is to discover if existing medications can be used to treat people with early-diagnosed COVID-19. The TOGETHER Trial was initiated on June of 2020. On January 20, 2021, TOGETHER enrolled its first patient. The TOGETHER Trial is a multi-platform, randomized, adaptive trial. The co-principal investigators of TOGETHER are Dr. Edward Mills and Dr. Gilmar Reis. Drugs trialed Hydroxychloroquine - effect not found, arm stopped. See trial results paper. Lopinavir/Ritonavir - effect not found, arm stopped. See trial results paper. Ivermectin - effect not found, arm stopped. Metformin - effect not found, arm stopped. See trial results paper. Fluvoxamine - intervention found effective. See trial results paper. Peginterferon Lambda - intervention found effective. Doxazosin - recruitment paused. Links togethertrial.com - website for the TOGETHER trial. Includes trial protocol design, statistical analysis plan and other information. TOGETHER Trial on Twitter.

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The TOGETHER Trial is a clinical trial platform evaluating repurposed drugs for early treatment of COVID-19. The TOGETHER Trial's aim is to discover if existing medications can be used to treat people with early-diagnosed COVID-19.

The TOGETHER Trial was initiated on June of 2020. On January 20, 2021, TOGETHER enrolled its first patient.

The TOGETHER Trial is a multi-platform, randomized, adaptive trial. The co-principal investigators of TOGETHER are Dr. Edward Mills and Dr. Gilmar Reis.

Drugs trialed

Hydroxychloroquine - effect not found, arm stopped. See trial results paper.
Lopinavir/Ritonavir - effect not found, arm stopped. See trial results paper.
Ivermectin - effect not found, arm stopped.
Metformin - effect not found, arm stopped. See trial results paper.
Fluvoxamine - intervention found effective. See trial results paper.
Peginterferon Lambda - intervention found effective.
Doxazosin - recruitment paused.

Drugs trialed

Hydroxychloroquine - effect not found, arm stopped. See trial results paper.
Lopinavir/Ritonavir - effect not found, arm stopped. See trial results paper.
Ivermectin - effect not found, arm stopped.
Metformin - effect not found, arm stopped. See trial results paper.
Fluvoxamine - intervention found effective. See trial results paper.
Peginterferon Lambda - intervention found effective.
Doxazosin - recruitment paused.

philipn / TOGETHER Trial 44e009344092f7898560b88c526675dec9494ebf

Drugs trialed

Links

Drugs trialed

Links