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The TOGETHER Trial is a clinical trial platform evaluating repurposed drugs for early treatment of COVID-19.  The TOGETHER Trial's aim is to discover if existing medications can be used to treat people with early-diagnosed COVID-19.

The TOGETHER Trial was initiated on June of 2020. On January 20, 2021, TOGETHER enrolled its first patient.

The TOGETHER Trial is a multi-platform, randomized, adaptive trial. The co-principal investigators of TOGETHER are Dr. Edward Mills and Dr. Gilmar Reis.

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The TOGETHER Trial is a clinical trial platform evaluating repurposed drugs for early treatment of COVID-19.  The TOGETHER Trial's aim is to discover if existing medications can be used to treat people with early-diagnosed COVID-19.

The TOGETHER Trial was initiated on June of 2020. On January 20, 2021, TOGETHER enrolled its first patient.

The TOGETHER Trial is a multi-platform, randomized, adaptive trial. The co-principal investigators of TOGETHER are Dr. Edward Mills and Dr. Gilmar Reis.

Drugs trialed

  • Hydroxychloroquine - effect not found, arm stopped.
  • Lopinavir/Ritonavir - effect not found, arm stopped.
  • Ivermectin - effect not found, arm stopped.
  • Metformin - effect not found, arm stopped.
  • Fluvoxamine - intervention found effective.
  • Peginterferon Lambda - intervention found effective.
  • Doxazosin - recruitment paused.

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