The TOGETHER Trial did not find hydroxychloroquine or lopinavir/ritonavir effective in reducing the need for hospitalization. Photo CC-BY Reis G et al.

The TOGETHER Trial is a clinical trial platform evaluating repurposed drugs for early treatment of COVID-19.  The TOGETHER Trial's aim is to discover if existing medications can be used to treat people with early-diagnosed COVID-19.

To date, the TOGETHER Trial has identified two potentially effective medications for COVID-19: Fluvoxamine and Peginterferon Lambda.

The TOGETHER Trial was initiated on June of 2020. On January 20, 2021, TOGETHER enrolled its first patient.

The TOGETHER Trial is a multi-platform, randomized, adaptive trial. The co-principal investigators of TOGETHER are Dr. Edward Mills and Dr. Gilmar Reis.

Drugs trialed